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found that elevated serum UA levels were associated with a lower risk of developing dementia (HR, 0.81

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A study based on Nrf2-KO (knockout of Nrf2) diabetic mice showed that syringaresinol inhibits pyroptosis caused by NLRP3/Caspase-1 in DN by activating the Nrf2/HO-1 signaling pathway [72]

In general, when hyperglycaemia is corrected in individuals with type 2 diabetes using a variety of interventions, including sulfonylureas and insulin, GIP sensitivity can be restored [32, 33]